Approach to novel functional foods for stress control 3. Establishment of stress-resistant rat model and its mechanism.

نویسندگان

  • Yutaka Nakaya
  • Masaki Morishima-Yamato
  • Kaori Ishida
  • Nagakatsu Harada
  • Masayuki Nakano
چکیده

A stress-resistant rat model was introduced. SPORTS (Spontaneously-Running-Tokushima-Shikoku) rats showed significantly shorter time of immobility in the forced swim test compared to control Wister rats. Increase norepinephrine concentration secondary to decreased activity of monoamine oxidase A (MAOA) in hippocampus was observed in this model rats. This model rats are considered to be useful for studying the mechanism of psychological stress.

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عنوان ژورنال:
  • The journal of medical investigation : JMI

دوره 52 Suppl  شماره 

صفحات  -

تاریخ انتشار 2005